Innotrain Products

nno-train was founded in 1998 as a diagnostics company in Frankfurt-Main with the aim of developing innovative diagnostic products and selling them with optimal customer training and high service standards. Inno-train was the first supplier worldwide to produce and sell molecular-biological IVD test systems for blood group diagnostics. The rapid expansion of the company made it necessary to move to the current company headquarters in Kronberg at the beginning of 2000 (HRB 5256, district court of Königstein/Taunus).

inno-train diagnostics GmbH is a provider of in-vitro diagnostics in the field of transfusion medicine and immunohaematology. The majority of the product portfolio was and is produced by inno-train itself. The products for HLA and blood group diagnostics that are essential for the success of the company are in-house developments.

As a supplier and producer of diagnostics, inno-train has been certified in accordance with DIN EN ISO 13485 for the design, manufacture and sale of in-vitro diagnostics since September 2003.

HLA-Ready Plate - Microlymphocytotoxicitytest

The microlymphocytotoxicity assay uses lymphocytes as the target. Viable cells are easily extracted from peripheral blood, lymph nodes, spleen, etc. This serologic assay measures cell death by the activation of complement (rabbit) in the presence of specific antigen-antibody combinations.

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HLA-Ready Gene - The SSP-PCR System

Integrated detection of the nullalleles A*24:09N, B*51:11N, C*04:09N, DRB4*01:03N, DRB5*01:08N

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HLA-Ready Gene for Disease Association

All HLA-Ready Gene kits for HLA disease associations contain a separate tube of validated Axi-Taq polymerase (100 U)

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HLA-SuBiTo® – The Sequencing

CE certified detection of HLA class I and II & B27 antigens

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HLA-FluoGene® – The Fluorescence PCR

FluoGene® is a unique method for molecular HLA-, RBC- and HPA typing combining all advantages of the SSP-PCR with the speed of endpoint fluorescence detection. The analysis is based on a specifically modified TaqMan® probe system by inno-train.

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HPA-FluoGene

FluoGene® is a unique method for molecular HLA-, RBC- and HPA typing combining all advantages of the SSP-PCR with the speed of endpoint fluorescence detection. The analysis is based on a specifically modified TaqMan® probe system by inno-train.

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HPA-Ready Gene

Human Platelet Antigen (HPA) are glycoproteins expressed on the thrombocyte membrane. Antibodies against the Human Platelet Antigens can cause immune reactions in the recipient's blood leading to the lysis of the transfused thrombocytes. In these cases the patient has to be provided with platelet concentrates without the antigen structure which is recognized by the anitbody.

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RBC-FluoGene

FluoGene® is a unique method for molecular HLA-, RBC- and HPA typing combining all advantages of the SSP-PCR with the speed of endpoint fluorescence detection. The analysis is based on a specifically modified TaqMan® probe system by inno-train.

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RBC-Ready Gene

Red Blood Cell-Ready Gene is inno-train's product line for analysis of erythrocyte blood groups based on the SSP-PCR method. Therefore these diagnostic systems represent the ideal complement to serolgoical blood group typing. The modular kit design offers an extensive choice for a gradual typing system depending on your problem.

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HiType – The Sequencing Software

The innovative and user-optimized Software for HLA sequencing analysis.

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BEXS 12 - DNA and Viral DNA/RNA Isolation

The Ready DNA Bead Kit is based on the DNA feature to adsorb on the surface of specially coated magnetic particles in the presence of chaotropic salts.

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DaraEx - anti-CD38 antibody neutralizing agent

Antibody based drugs can disturb serological blood group testing since the examined antigens can be masked by the therapeutic antibodies.

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Recombinant blood group antigens for serology

The detection of antibodies to blood group antigens is crucial in pre and posttransfusion testing to allow for adequate blood supply of patients requiring blood transfusions.

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